Bioventix plc (BVXP), a UK company specialising in the development and commercial supply of high-affinity monoclonal antibodies for applications in clinical diagnostics, announces that the Company was notified on 19 November 2021 that on 15th November 2021 Bruce Hiscock, Chief Financial Officer of the Company, purchased a total of 5 ordinary shares of 5 pence each in the Company (“Ordinary Shares”), at an average price of 3,687 pence per Ordinary Share (the “Purchase”). The shares were purchased under a dividend reinvestment plan (DRIP).
Following the Purchase, Bruce Hiscock has a beneficial interest in 421 Ordinary Shares, representing approximately 0.01 per cent. of the issued share capital of the Company.
The notification below, made in accordance with the requirements of the EU Market Abuse Regulation, provides further details.
For further information please contact:
| Bioventix plc Peter Harrison |
Chief Executive Officer | Tel: 01252 728 001 |
| finnCap Ltd Geoff Nash/Simon Hicks Alice Lane |
Corporate Finance ECM |
Tel: 020 7220 0500 |
This announcement contains inside information for the purposes of Article 7 of the Market Abuse Regulation (EU) 596/2014 as it forms part of UK domestic law by virtue of the European Union (Withdrawal) Act 2018 (“MAR”), and is disclosed in accordance with the company’s obligations under Article 17 of MAR.
Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them
| 1 | Details of the person discharging managerial responsibilities / person closely associated | |
| a) | Name | Bruce Hiscock |
| 2. | Reason for the Notification | |
| a) | Position/status | Chief Financial Officer |
| b) | Initial notification/Amendment | Initial notification |
| 3. | Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor | |
| a) | Name | Bioventix Plc |
| b) | LEI | 213800225MHX7LZQY108 |
| 4. | Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted | |
| a) | Description of the Financial instrument, type of instrument | Ordinary Shares of 5 pence each |
| Identification code | GB00B4QVDF07 | |
| b) | Nature of the transaction | Purchase of Ordinary Shares |
| c) | Price(s) and volume(s) | 5 Ordinary Shares of 3,687 pence each |
| d) | Aggregated information:
· Aggregated volume · Price |
5 Ordinary Shares of 3,687 pence each |
| e) | Date of the transaction | 15 November 2021 |
| f) | Place of the transaction | London Stock Exchange, AIM Market (XLON) |
Bioventix plc (BVXP), a UK company specialising in the development and commercial supply of high-affinity monoclonal antibodies for applications in clinical diagnostics, confirms that its Annual Report and Accounts for the year ended 30 June 2021 and the Notice of Annual General Meeting (“AGM”) has been posted to shareholders.
A PDF version of the 30 June 2021 Annual Report can be downloaded here.
Notice of AGM to be held 9th December 2021 can be found here and proxy forms available here.
The AGM will be held at Farnham Castle, Farnham, Surrey, GU9 0AG at 2.00 p.m. on 9 December 2021.
The Board continues to monitor the situation surrounding COVID-19 and the advice from the Government on public gatherings. If the Government’s guidance changes at any point prior to the AGM, such that shareholders are unable to attend in person, the Company will update shareholders through an announcement to the London Stock Exchange and on the Company’s website. In light of this uncertainty, the Board strongly encourages shareholders to submit a proxy vote in advance of the AGM and to appoint the Chairman of the AGM as their proxy, rather than a named person who, if circumstances change, may not the able to attend the AGM.
For further information please contact:
| Bioventix plc
Peter Harrison Bruce Hiscock |
Chief Executive Officer Chief Financial Officer |
Tel: 01252 728 001 |
| finnCap Ltd
Geoff Nash/Simon Hicks Alice Lane |
Corporate Finance ECM |
Tel: 020 7220 0500 |
About Bioventix plc:
Bioventix (www.bioventix.com) specialises in the development and commercial supply of high-affinity monoclonal antibodies with a primary focus on their application in clinical diagnostics, such as in automated immunoassays used in blood testing. The antibodies created at Bioventix are generated in sheep and are of particular benefit where the target is present at low concentration and where conventional monoclonal or polyclonal antibodies have failed to produce a suitable reagent. Bioventix currently offers a portfolio of antibodies to customers for both commercial use and R&D purposes, for the diagnosis or monitoring of a broad range of conditions, including heart disease, cancer, fertility, thyroid function and drug abuse. Bioventix currently supplies antibody products and services to the majority of multinational clinical diagnostics companies. Bioventix is based in Farnham, UK and its shares are traded on AIM under the symbol BVXP.
Director’s report and financial statements for the year ended 30th June 2021.
To download this report as a PDF file click here
Bioventix plc (BVXP) announces its audited results for the year ended 30 June 2021
TR-1: Notification of major interest in shares. To download this report as a PDF file click here.
TR-1: Notification of major interest in shares. To download this report as a PDF file click here.
TR-1: Notification of major interest in shares. To download this report as a PDF file click here.
Background: Circulating secretoneurin (SN) concentrations, as measured by established radioimmunoassay (RIA), risk stratify patients with cardiovascular disease. We now report data for a recently developed research-use-only SN enzyme- linked immunosorbent assay (ELISA) in patients with sus- pected acute coronary syndrome (ACS).
Methods: SN ELISA was developed according to industry standards and tested in 401 unselected chest pain patients. Blood samples were drawn <24 h from admission, and we adjudicated all hospi- talizations as ACS or non-ACS. The mean follow-up was 6.2 years.
Results: SN ELISA with 2 monoclonal sheep anti-SN antibodies has a measuring range of 10–250 pmol/L and demonstrates excellent analytical precision and accuracy across the range of SN concentrations. SN measured by ELI- SA and RIA correlated in the chest pain patients: rho = 0.39, p < 0.001. SN concentrations were higher in ACS patients (n = 161 [40%]) than in non-ACS patients (n = 240) for both assays, with an area under the curve (AUC) of 0.66 (95% CI: 0.61–0.71) for ELISA and 0.59 (0.54–0.65) for RIA. SN concen- trations were also higher in nonsurvivors (n = 65 [16%]) than survivors, with an AUC of 0.72 (0.65–0.79) for ELISA versus 0.64 (0.56–0.72) for RIA, p = 0.007, for difference between as- says. Adjusting for age, sex, blood pressure, previous myo- cardial infarction, atrial fibrillation, and heart failure in mul- tivariable analysis, SN concentrations as measured by ELISA, but not RIA, remained associated with mortality, with a haz- ard ratio of 1.71 (1.03–2.84), p = 0.038.
Conclusions: The nov- el SN ELISA has excellent performance, higher AUC for diag- nosis, and superior prognostic accuracy compared to the es- tablished RIA in chest pain patients.
Interim results can be found here and are as stated below.
Highlights
CHAIRMAN AND CHIEF EXECUTIVE’S STATEMENT
Business review
The continuing global pandemic has, without doubt, affected the activity within diagnostic pathways in hospitals and clinics around the world to which our business is intrinsically linked. Not only have medical care resources been diverted to cope with COVID-19 patients but, even where capacity remains, there is ongoing evidence that patients are choosing not to present to healthcare professionals or not to enter diagnostic pathways. We are therefore relatively pleased to announce our unaudited interim results for the six-month period ended 31 December 2020 in which our revenues for the half-year of £5.2 million (2019: £5.1 million) were maintained at a similar level to those for the same period of the previous year.
Total profits before tax for the half-year decreased by 9% to £3.7 million (2019: £4.1 million), most of the reduction being created by exchange rate-related charges of £0.27m. The cash balances at 31 December 2020 also remained at a very similar level, finishing the period up by £0.3 million at £5.8 million.
As reported previously, vitamin D antibody sales were not expected to match the growth rates seen in recent financial years and a plateau in the downstream global vitamin D assay market had been anticipated. The very modest growth seen was perhaps better than could have been anticipated.
Our antibodies for thyroid disease diagnostics (T3) and others for fertility diagnostics (estradiol, progesterone and testosterone) form part of routine diagnostics for chronic conditions which are often not life-threatening. We believe that such diagnostic tests have experienced lower volumes in pandemic affected areas and this has had a small impact on our own revenues.
Sales relating to troponin antibodies grew significantly once again during the period. The continued roll-out of high sensitivity troponin tests provides further encouragement for our future sales in this area.
Our research activities continue in line with the plans described in the 2020 annual report. Whilst we will report further on these various projects with our full year results, we are particularly pleased with the development of our pollution exposure assay. We hope to have a prototype urine lateral flow test featuring in a field trial at a UK industrial site later in 2021. The intention is to measure and upload the lateral flow test results directly to health and safety operatives at the site through a phone-app camera reader system.
Regarding the use of SMAs to mitigate against the effect of biotin vitamin supplements on certain blood tests, we sent samples of “blocker” antibodies to customers late in 2020. We have received early positive feedback on the performance of these blockers from some customers. During 2021, we will continue to receive feedback and consider further the possible commercial development of these blockers where bulk manufacture at low cost will be important.
In December 2020, we sent samples of THC (the active ingredient in cannabis or marijuana) antibodies to a few selected customers who are interested in improving their THC lateral flow assays for saliva. The early feedback from these customers has been encouraging and we expect to gather more feedback during the year.
With the exception of COVID-19, the overall context of the business and the landscape in which we operate has not materially changed since the 2020 annual report and we draw the attention of any new shareholders to this report.
We have continued with the development of our Farnham laboratory. The work on our manufacturing facilities and technology development laboratory has been completed and we are now fully operational. The last remaining phase of the development work (cost ~£70k) is due to start imminently.
Bioventix has demonstrated that it is a resilient business and, notwithstanding our comments regarding the impact of the COVID-19 pandemic, our plan is to continue to follow our established dividend policy. For the period under review, the Board is pleased to announce a first interim dividend of 43p per share which represents a 20% increase on last year (36 pence per share).
The shares will be marked ex-dividend on the 8 April 2021 and the dividend will be paid on 23 April 2021 to shareholders on the register at close of business on 9 April 2021.
In conclusion, we are encouraged by the performance of Bioventix for the current half-year and pleased with the continued success of our vitamin D antibody and core antibody business. We remain optimistic about our troponin revenues and the success of these high sensitivity troponin products around the world and we look forward to reporting further progress in the second half of the year.
For further information please contact:
| Bioventix plc
Peter Harrison Chief Executive Officer
|
Tel: 01252 728 001 |
| finnCap Ltd
Geoff Nash/Simon Hicks – Corporate Finance Alice Lane – ECM |
Tel: 020 7220 0500 |
About Bioventix plc:
Bioventix (www.bioventix.com) specialises in the development and commercial supply of high-affinity monoclonal antibodies with a primary focus on their application in clinical diagnostics, such as in automated immunoassays used in blood testing. The antibodies created at Bioventix are generated in sheep and are of particular benefit where the target is present at low concentration and where conventional monoclonal or polyclonal antibodies have failed to produce a suitable reagent. Bioventix currently offers a portfolio of antibodies to customers for both commercial use and R&D purposes, for the diagnosis or monitoring of a broad range of conditions, including heart disease, cancer, fertility, thyroid function and drug abuse. Bioventix currently supplies antibody products and services to the majority of multinational clinical diagnostics companies. Bioventix is based in Farnham, UK and its shares are traded on AIM under the symbol BVXP.
This announcement contains inside information for the purposes of Article 7 of the Market Abuse Regulation (EU) 596/2014 as it forms part of UK domestic law by virtue of the European Union (Withdrawal) Act 2018 (“MAR”), and is disclosed in accordance with the company’s obligations under Article 17 of MAR.
Unaudited interim results for the six months ended 31st December 2020